Opportunities and Challenges of circular RNA in basic research, Application and industrial transformation: An in-depth discussion and prospect!

"The 7th circRNA Research and Industry Forum" was successfully held in Guangzhou on November 11-12, 2023! We aim to provide an exchange platform to share the latest circRNA research results, discuss cutting-edge technical methods, and promote the development and application of circRNA in the biomedical industry.

Over the past few years, there has been remarkable progress in circRNA research, revealing its important role in gene expression and regulation. Today, with the advancement of technology and in-depth research, we have begun to use circRNA as a biomarker for disease diagnosis, as well as a new target for drug development. At the same time, by combining circRNA research with advanced technologies such as artificial intelligence, we are starting a new wave of biomedical innovation.

In this context, we specially planned a roundtable discussion to bring together top experts and industry leaders across disciplines to discuss circRNA's future development strategies, technology challenges and transformation opportunities. We are convinced that such dialogue and collision will not only promote the basic research of circRNA, but also accelerate its practical application in medicine, health, biotechnology and other fields. Let's take a step into this roundtable discussion, listen to the insights and insights of experts, and explore the infinite possibilities of circRNA.

The high-quality development of circRNA from basic research to industrial transformation

The high-quality development of circRNA from basic research to industrial transformation

On the 11th, Chief Professor, Southeast University Prof. Yao Honghong, Prof. Yang Baihua, Professor of Experimental Medicine and Pathology, University of Toronto, Canada; Prof. Li Xiangdong, Professor of College of Biological Sciences and Medicine, University of Science and Technology of China; Prof. Peng Yong, Professor of State Key Laboratory of Biological Therapy, West China Hospital, Sichuan University; The topic of "High-quality development of circRNA from basic research to industrial transformation" was discussed.

The meeting mainly discussed the problems of circular RNA in basic research, application and industrial transformation. In terms of basic research, the key issues to be solved include the specificity of protein expression and the dynamic regulation of RNA structure. In terms of applications, circular RNA can be used as a diagnostic marker and is expected to be a tool for minimally invasive or non-invasive diagnosis. In terms of industrial transformation, problems such as delivery and scale production need to be solved, and the emergence of circular RNA drugs may be predicted in the future.

Opportunities and challenges of circular RNA therapy

On the 12th, Mr. Zhang Maolei, CTO of Geisai Biology, Mr. Yang Yun, CTO of Ring Code Biology, Mr. Gao Lu, CEO of Yuanyin Biology, Mr. Dai Dongsheng, CEO of Youhuan Biology, and Mr. Xu Congcong, young Distinguished Professor of Suzhou University, had a lively and multi-dimensional discussion on the topic of "Opportunities and Challenges of circular RNA therapy".

The meeting mainly discussed key issues such as the industrialization prospect of circular RNA, industrial chain construction, and delivery, as well as specific practices such as how to find blockbuster drug pipelines and promote clinical progress. The teachers believe that the industrialization of circular RNA has broad development prospects, but it needs to solve the problems at the process level and the bottleneck of industrial chain construction. They suggested strengthening industry-university-research-medical cooperation, promoting innovative drug research and development, and solving circulation problems to promote the development and application of circular RNA therapy.